Biosensors and Medical Devices Development at VSB Technical University of Ostrava

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1 VŠB TECHNICAL UNIVERSITY OF OSTRAVA FACULTY OF ELECTRICAL ENGINEERING AND COMPUTER SCIENCE Biosensors and Medical Devices Development at VSB Technical University of Ostrava Ing. Martin Černý Ph.D. and BME team

2 Biomedical Engineering at VSB - TUO Education Bc. study students Ing. (MSc.) study students Research team 14 people (incl. Ph.D. students) directly in BME 40 people (incl. Ph.D. students) at department of Cybernetics and Biomedical Engineering (Cybernetics, Embedded systems, Virtual Instrumentation) Areas of Interest Biosensors Medical Devices Development Biosignal processing Telemedicine applications

3 Cotton fabrics were coated with Polyaniline (PANI), Polypyrrole (PPy) and with combinations of these two conducting polymers (double layer) Coated cotton fabrics were used as sensors to collect electrical response from Venus Flytrap plant PANI and PPy are regarded as mixed conductors having both ionic and electronic conduction [1-3] Paradigm of the use of conducting polymers in monitoring of plant neurobiology The method used is compared with the standard method Ag/AgCl electrode with conducting gel

4 Method (A) Clip electrode with coated cotton fabric (B) Non-polarizable Ag/AgCl surface electrode connected to the protruding strip of coated cotton fabric (C) Reference electrode (D) Plastic stick used for stimulation

5 Results Series of action potentials, PPy+PANI All cotton fabrics coated with PANI, PPy and their combinations have been able to collect and transfer the electrical response

6 Conclusions No significant differences among fabrics coated with different conducting polymers PANI, PPy, PANI+PPy, and PPy+PANI were observed: The trap (leaf) is a three-dimensional structure, contact area strongly varied during measurements from one another Even the lowest conductivity (single layer) is high enough for the recording of electrical signals in plants Cotton fabrics coated with conducting polymers are definitely comparable to the standard method: + Very good results at both single and series response monitoring + No need of conducting gel + No risk of tissue damage caused by the conducting gel + Simple and cost-effective preparation process - Slightly lower signal to noise ratio

7 Electrosurgical tools for non-linear cuts Based on stadardized tools Innovative shape of the tool = less of damaged tissue of liver

8 From idea and model

9 through realization, tests

10 Patent, publication and licence

11 Telemedicine applications Living Laboratory Flat for testing of remote home care devices and telemedicine solutions Sensing floor Ciradian rhythms monitoring

12 Innovation of rehabilitation device Implementace inerciálního senzoru do kruhové výseče Přesné měření náklonu Přesné měření otáčení Přenos dat pomocí Bluetooth 4

13 Stávající stav projektu Klinická studie na FN Ostrava Kvalifikační práce na VŠB TUO a LF OU Testování pomůcky na pracovišti firmy AGEL a na UP Olomouc

14 Příklad aplikace inerciálního senzoru Spolupráce s FN Ostrava, klinika léčebné rehabilitace Řešitelé za FNO: Mgr. Mariana Zádrapová Mgr. Iva Chwalková MUDr. Irina Chmelová, Ph.D., MBA Řešitelé za VŠB TU Ostrava Ing. Martin Černý, Ph.D. Ing. Maroš Šmondrk Ing. Jana Krohová

15 Inovace kruhové výseče - SW Tvorba rehabilitačních programů s biofeedbackem Diagnostika průběhu rehabilitačního cvičení Analýza měřených dat pro diagnostiku rehabilitace Rehabilitační hry pro děti

16 Thank you for your attention Autors: Ing. Martin Černý, Ph.D. Ing. Marek Penhaker, Ph.D. and BME team Contact: