Collabora'on between Coopera'on: Universi'es and Industry in Czech Republic Kamil Kuča
Content CTBT Coopera'on with Companies Biomedical Research Center ( spin- off )
CTBT
Hradec Kralove - Biomedicine University Hospital HK Faculty of Medicine LFHK UH HK Faculty of Military Health Sciences FVZ Pharmaceutical faculty Faf UHK Faculty of Science UHK Faculty of Informactics and Managment UHK (Biomedical Informatics Center)
CTBT responsible University Hospital Hradec Kralove University of Hradec Kralove Faculty of Military Health Sciences
TTO Call Czech Republic Project University Budget Centrum transferu biomedicínských technologií HK Fakultní nemocnice Hradec Králové Univerzita Hradec Králové Fakulta vojenského zdravotnictví 24 666 900 Kč Centrum transferu technologií a znalosm UPa Univerzita Pardubice 46 833 204 Kč Jihočeské Univerzitní a Akademické CTT Jihočeská univerzita v Českých Budějovicích 56 496 832 Kč InovaNET České vysoké učení technické v Praze 33 620 189 Kč Centrum pro inovace a transfer technologií Fyzikální ústav AV ČR, v.v.i. 50 910 800 Kč Transfer technologií na Masarykově univerzitě Masarykova univerzita 55 283 691 Kč Centrum Transferu Technologií MENDELU Mendelova univerzita v Brně 24 116 450 Kč Rozvoj CTT na UTB ve Zlíně Univerzita Tomáše Ba' ve Zlíně 16 186 009 Kč Rozvoj a stabilizace systému TT VŠB- TUO Vysoká škola báňská - Technická univerzita Ostrava 35 196 283 Kč
CTBT in numbers Budget Personal th. Kč % CTBT per. CTBT FTE Tech. Sc. Tech. Sc. FTE Sum 24 666 100% 6 5,5 11 1,2 FN HK 20 964 85% 5 5 5 0,6 UHK 2 771 11% 1 0,5 3 0,3 FVZ 931 4% 0 0 3 0,3 Project 100% Project Sustainability Paid by partners and CTBT income CTBT Income and partners 07/12-06/15 07/15-06/20 07/20 -?
CTBT goal Intellectual property, Spin-off setup, Management of service research, Searching for results which could be applied in the real praxis, PR for FN HK, UHK a FVZ UO, Making contacts with companies, Searching for reasults.
EVALUATION OF INTERNAL PROJECT Are in the project results which could be commercialized Discussion with scientists
SCIENTIST evaluavon
CooperaVon with Companies
Who is Coming? SME Universi'es Investors
Company request? Services Mutual research Technology agency projects Consulta'ons University Approval/Personal Approval connec'on of product with Ins'tute/Well- known Scien'sts Searching for accredited laboratories
Types of cooperavon Firstly as service Then mutual coopera'on - then par'cipa'on on results is expected
How do we get contacts? scien'fic mee'ngs friends (TTO, scien'sts, ) CTBT Web site students and employee research stay
What are we offering Quality scien'sts Environment - ready to work on different topics
Project for CooperaVon Czech technology agency Projects Pre- seed projects (MSMT)
Biomedical Research Center
History April 2011 - Established à To prevent ouwlow of scien'sts (3 full posi'ons divided into 6 people) February 2012 - Laboratory facility EU postdoc program started (4 full posi'ons gained) October 2013-30 empoyees (senior and junior scien'sts, PhD students, lab. assistants; total 3.2 posivons full/part 'me) www.fnhk.cz/cbv
Aims " Support basic research in the Hospital (drug development, analysis, assessment etc.) " Service for the clinics and applied research (proteomics, pharmacokine8cs etc.) " EducaVon (pre and postgraduated students, interships, seminars)
Funding Projects: Currently solving 11 project (including internal) 6 internal coopera'ons (within Hospital) 8 external coopera'ons (in CZ) Grant agencies: Grant Agency of CZ, Grant agencies under Ministry of Health, Defence, Educa'on etc. Private sector (organic synthesis, cytotoxicity, acute toxicity etc) Incomes: " Projects (10-20% for the hospital) " Publica'ons (depending on the IF) " Services for fee " Licensing???...what we get, we need to pay back
Topics Představení proteomické skupiny Centra Biomedicínského Výzkum Proteomics D rug Chemical synthesis In vitro biologial assessment D eve l o p m ent In vivo assesment, toxicity Pharmacokinetics
DRUG DEVELOPMENT 12-15 years, aprox. 1 mld USD BRC Drug discovery Preclinical Trials Clinical trials (I.- III. phase) Prac'cal use (IV. phase)
Pipeline for drug development CWA An'dotes Design and Synthesis In- vitro evaluavon Toxicity PharmacokineVcs In- vivo Targeted synthesis 1st selecvon 2nd selecvon Alzheimer s Vaccine Adjuvans? Drug candidates - recommendation for preclinical trials, commercialization Detergents
BRC - PROTEOMICS Clinical proteomics Quan'ta've and qualita've descrip'on of the protein content in the samples using LCMS ExploraVve analysis What pro'ens are in a sample?= idenvficavon What is the difference in quan''es of different proteins in a samples (treated vs non- treated group) = quanvficavon Targeted analysis I know what I m looking for and what is the level of this protein in different samples
Offering Services Joint research with companies Special analysis Preclinical research Products evaluation Articles for PR Consultation
Thank you very much for your a~en'on